Higure, Il Vento Immobile

If Higure deals first strike damage (or the first part of double strike damage), the triggered ability would resolve before regular combat damage, and the searched-for Ninja would be able to get swapped with an unblocked creature and still deal its regular damage.

If Higure deals regular combat damage and you use its ability to search for another Ninja, that card won't be in your hand in time to activate its ninjutsu ability to put it onto the battlefield and deal damage. However, the card you searched for could still be swapped for an unblocked creature, including Higure, as long as you activate its ninjutsu ability before the end of combat.